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- SPECIES: Human
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: Human full-length NMNAT1 (aa 1-279) is fused at the N-terminus to a His-tag.
- FUSION TAG: His Tag
- APPLICATION NOTE: This recombinant proteins is for research use only.
- BIOLOGICAL ACTIVITY: >5U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1umol of NAD+ per min.
Properties
- PURITY: >95% (SDS-PAGE)
- PHYSICAL STATE: Liquid
- BUFFER: In 50mM sodium phosphate, pH8.0, containing 300mM sodium chloride, 2mM DTT and 10% glycerol.
- CONCENTRATION: ~1mg/ml
- STORAGE CONDITIONS: Working aliquots are stable for up to 3 months when stored at -20°C.
Additional Info
- NCBI OFFICIAL SYMBOL: NMNAT1
- ADDITIONAL NAMES: Nicotinamide Mononucleotide Adenylyltransferase 1, NMN Adenylyltransferase 1, NaMN Adenylyltransferase 1, EC 2.7.7.1
- Protein Accession Number: Q9HAN9
- PROTEIN GI NUMBER: 20070321
- NCBI GENE ID NUMBER: 64802
Background
- Nuclear NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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