Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 208-457 of human NFS1 (NP_066923.3).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, IHC, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200 - POSITIVE CONTROL 1: HepG2
- POSITIVE CONTROL 2: SKOV3
- POSITIVE CONTROL 3: Mouse kidney
- POSITIVE CONTROL 4: Mouse heart
- POSITIVE CONTROL 5: Rat liver
- POSITIVE CONTROL 6: Rat kidney
- PREDICTED MOLECULAR WEIGHT: Observed: 50kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: NFS1
- ADDITIONAL NAMES: NFS1, IscS, NIFS, HUSSY-08
- NCBI GENE ID NUMBER: 9054
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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