- SPECIES: Mouse
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: Mouse Nampt (visfatin/PBEF) (aa 1-491) is fused at the C-terminus to a His-tag.
- FUSION TAG: His Tag
- APPLICATION NOTE: This recombinant proteins is for research use only.
- BIOLOGICAL ACTIVITY: Shows adipogenic effects in stimulated differentiating 3T3-L1 cells.
- PURITY: >90% (SDS-PAGE).
Endotoxin level is less than 1EU/ μg purified protein (LAL test; Lonza).
- PHYSICAL STATE: Lyophilized
- BUFFER: Lyophilized from 0.2um-filtered solution in PBS, pH 7.2. Reconstitute in distilled water.
- STORAGE CONDITIONS: Working aliquots are stable for up to 3 months when stored at -20°C.
- NCBI OFFICIAL SYMBOL: Nampt
- ADDITIONAL NAMES: Pre-B Cell Colony Enhancing Factor 1, PBEF1, Nicotinamide Phosphoribosyltransferase
- Protein Accession Number: Q99KQ4
- PROTEIN GI NUMBER: 68565929
- NCBI GENE ID NUMBER: 59027
- Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
- FOR RESEARCH USE ONLY
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CATALOG NUMBER: 90-009
- Size: 50 ug
- List Price: $480.00
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