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NALP14 Antibody
CATALOG NUMBER: 5975- Clonality: Polyclonal
- Tested Applications: ELISA, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 0.02 mg | 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: NALP14 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP14.
The immunogen is located within amino acids 200 - 250 of NALP14. - CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, WB
- APPLICATION NOTE: NALP14 antibody can be used for detection of NALP14 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. - POSITIVE CONTROL 1: Cat. No. 1463 - Rat Brain Tissue Lysate
Properties
- PURIFICATION: NALP14 Antibody is affinity chromatography purified via peptide column.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: NALP14 Antibody is supplied in PBS containing 0.02% sodium azide.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: NALP14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: NLRP14
- ADDITIONAL NAMES: NALP14 Antibody: NOD5, PAN8, GC-LRR, NALP14, CLR11.2, NOD5, NACHT, LRR and PYD domains-containing protein 14, Nucleotide-binding oligomerization domain protein 5
- Protein Accession Number: NP_789792
- PROTEIN GI NUMBER: 28827813
- NCBI GENE ID NUMBER: 338323
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- NALP14 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.
- 1: Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.
- 2: Tian X, Pascal G, and Monget P. Evolution and functional divergence of NLRP genes in mammalian reproductive system. BMC Evol. Biol.2009; 9:202.
- 3: Westerveld GH, Korver CM, van Pelt AMM, et al. Mutations in the tesits-specific NALP14 gene in men suffering from spermatogenic failure. Hum. Reprod.2006; 21:3178-84.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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