- Trial Size
MYBPC1 Antibody
CATALOG NUMBER: 5649- Clonality: Polyclonal
- Tested Applications: ELISA, IHC-P
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 0.02 mg | 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: MYBPC1 antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human MYBPC1.
The immunogen is located within the last 50 amino acids of MYBPC1. - CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, IHC-P
- APPLICATION NOTE: MYBPC1 antibody can be used for detection of MYBPC1 by immunohistochemistry at 5 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. - POSITIVE CONTROL 1: Cat. No. 1375 - Human Skeletal Muscle Tissue Lysate
Properties
- PURIFICATION: MYBPC1 Antibody is affinity chromatography purified via peptide column.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: MYBPC1 Antibody is supplied in PBS containing 0.02% sodium azide.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: MYBPC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: MYBPC1
- ADDITIONAL NAMES: MYBPC1 Antibody: LCCS4, MYBPCC, MYBPCS, Myosin-binding protein C, slow-type, C-protein, skeletal muscle slow isoform, Slow MyBP-C
- Protein Accession Number: NP_002456
- PROTEIN GI NUMBER: 45976288
- NCBI GENE ID NUMBER: 4604
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- MYBPC1 Antibody: Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the slow-type isoform designated MYBPC1. Both the fast-type (MYBPC2) and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. Multiple isoforms of MYBPC1 are known to exist, and are present in varying amounts in different skeletal muscles. It is thought that the MYBPC1 slow subfamily may play important roles in the assembly and stabilization of sarcomeric M- and A-bands and regulate the contractile properties of the actomyosin filaments.
- 1: Furst DO, Vinkemeir U and Weber K. Mammalian skeletal muscle C-protein: purification from bovine muscle, binding to titin and the characterization of a full-length human cDNA. J. Cell Sci. 1992; 102:769-78.
- 2: Weber FE, Vaughan KT, Reiach FC, et al. Complete sequence of human fast-type and slow-type muscle myosin-binding-protein C (MyBP-C). Differential expression, conserved domain structure and chromosome assignment. Eur. J. Biochem. 1993; 216:661-9.
- 3: Ackermann MA and Kontrogianni-Konstantopoulous A. Myosin binding protein-C slow: an intricate subfamily of proteins. J. Biomed. Biotech. 2010; 2010:652065
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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