Specifications
- SPECIES: Human
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: aa. 1-344
- TESTED APPLICATIONS: E, MS, WB
- APPLICATION NOTE: This recombinant protein can be used for WB, ELISA, MS.
- PREDICTED MOLECULAR WEIGHT: 39.56 kDa (Calculated)
Properties
- PURITY: >95%
- PHYSICAL STATE: Liquid
- BUFFER: 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3
- STORAGE CONDITIONS: Store in working aliquots at -70°C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Additional Info
- NCBI OFFICIAL SYMBOL: MTHFD2
- ADDITIONAL NAMES: NMDMC, NMDMC
- Protein Accession Number: NP_006627
- PROTEIN GI NUMBER: 5729935
- NCBI GENE ID NUMBER: 10797
Background
- This is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.
Disclaimer
- FOR RESEARCH USE ONLY
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