test: e MSK1 (phospho Ser212) Antibody - Cat. No. 79-984 | ProSci
Close Hamburger Menu Close Hamburger Menu
Home / Human / MSK1 (phospho Ser212) Antibody
MSK1 (phospho Ser212) Antibody
MSK1 (phospho Ser212) Antibody

MSK1 (phospho Ser212) Antibody

CATALOG NUMBER: 79-984
  • Clonality: Polyclonal
  • Tested Applications: WB
  • Host Species: Rabbit
  • Species Reactivity: Human, Mouse
  • Conjugate: Unconjugated
  • Size: 0.1 mg

Specifications

  • HOST SPECIES: Rabbit
  • SPECIES REACTIVITY: Human, Mouse
  • IMMUNOGEN: MSK1 (phospho Ser212) antibody was raised against a peptide sequence around phosphorylation site of serine 212 (A-Y-S (p)-F-C) derived from Human MSK1.
  • CONJUGATE: Unconjugated
  • TESTED APPLICATIONS: WB
  • APPLICATION NOTE: Western Blot: 1:500~1:1000
  • SPECIFICITY: The antibody detects endogenous level of MSK1 only when phosphorylated at serine 212.
  • PREDICTED MOLECULAR WEIGHT: 90 kDa

Properties

  • PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • CLONALITY: Polyclonal
  • ISOTYPE: IgG
  • PHYSICAL STATE: Liquid
  • BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • CONCENTRATION: 1 mg/mL
  • STORAGE CONDITIONS: Store antibody at -20°C for up to one year.

Additional Info

  • NCBI OFFICIAL SYMBOL: RPS6KA5
  • ADDITIONAL NAMES: polypeptide 5, KS6A5, MSPK1, RPS6KA5, RLPK
  • Protein Accession Number: NP_004746.2
  • PROTEIN GI NUMBER: 32528295
  • NCBI GENE ID NUMBER: 9252

Background

  • Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14).
  • 1: McCoy CE, et al. (2007) Biochem J 402, 491-501
  • 2: McCoy CE, et al. (2005)Biochem J 387, 507-17

Disclaimer

  • FOR RESEARCH USE ONLY
    For additional information, visit ProSci's Terms & Conditions Page.
  • Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER: 79-984

  • Size: 0.1 mg
  • List Price: $335.00
Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services 

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products
HIV-1 p24 Antibody [10A2] (biotin)
HIV-1 p24 Antibody [10A2] (biotin)

CATALOG NUMBER: PM-7371-biotin

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [8D7E11] (biotin)
HIV-1 p24 Antibody [8D7E11] (biotin)

CATALOG NUMBER: PM-7367-biotin