Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human MRPL13 (NP_054797.2).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IHC: 1:100 - 1:200 - POSITIVE CONTROL 1: SH-SY5Y
- POSITIVE CONTROL 2: HL-60
- POSITIVE CONTROL 3: HT-29
- POSITIVE CONTROL 4: A-549
- POSITIVE CONTROL 5: HeLa
- POSITIVE CONTROL 6: Mouse kidney
- PREDICTED MOLECULAR WEIGHT: Observed: 20kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: MRPL13
- ADDITIONAL NAMES: L13, L13A, L13mt, RPL13, RPML13, 39S ribosomal protein L13, mitochondrial, MRP-L13, mitochondrial large ribosomal subunit protein uL13m
- NCBI GENE ID NUMBER: 28998
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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