Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This MRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the Central region of human MRC2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 167 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: MRC2
- ADDITIONAL NAMES: C-type mannose receptor 2, C-type lectin domain family 13 member E, Endocytic receptor 180, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein, UPAR-associated protein, Urokinase receptor-associated protein, CD280, MRC2, CLEC13E, ENDO180, KIAA0709, UPARAP
- Protein Accession Number: Q9UBG0
- PROTEIN GI NUMBER: 317373394
- NCBI GENE ID NUMBER: 9902
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- MRC2 is a recycling endocytic receptor that functions incell motility and remodeling of the extracellular matrix bypromoting cell migration and uptake of collagens for intracellulardegradation (Wienke et al., 2007 [PubMed 17974964]).[supplied byOMIM].
- 1: Messaritou, G., et al. J. Cell. Sci. 122 (PT 22), 4042-4048 (2009) :
- 2: Wu, X., et al. Cancer Prev Res (Phila Pa) 2(7):617-624(2009)
- 3: Wienke, D., et al. Cancer Res. 67(21):10230-10240(2007)
- 4: Sulek, J., et al. J. Histochem. Cytochem. 55(4):347-353(2007)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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