Mouse Frk Antibody
CATALOG NUMBER: 58-031- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Mouse
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Rat
- IMMUNOGEN: This Mouse Frk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-491 amino acids from the C-terminal region of mouse Frk.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 59 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: Frk
- ADDITIONAL NAMES: Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk
- Protein Accession Number: Q922K9
- NCBI GENE ID NUMBER: 14302
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity).
- 1: Akerblom, B., et al. Mol. Cell. Endocrinol. 270 (1-2), 73-78 (2007) :
- 2: Nishimura, M., et al. DNA Res. 11(5):315-323(2004)
- 3: Sharov, A.A., et al. PLoS Biol.(3), E74 (2003) :
- 4: Cowen, M.S., et al. Alcohol. Clin. Exp. Res. 27(8):1213-1219(2003)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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