Mouse Dyrk1b Antibody
CATALOG NUMBER: 57-862- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Mouse
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Human
- IMMUNOGEN: This Mouse Dyrk1b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-403 amino acids from the Central region of mouse Dyrk1b.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 69 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: Dyrk1b
- ADDITIONAL NAMES: Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Dyrk1b
- Protein Accession Number: Q9Z188
- NCBI GENE ID NUMBER: 13549
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activity. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.
- 1: Janumyan, Y., et al. J. Biol. Chem. 283(49):34108-34120(2008)
- 2: Munton, R.P., et al. Mol. Cell Proteomics 6(2):283-293(2007)
- 3: Mercer, S.E., et al. J. Biol. Chem. 280(27):25788-25801(2005)
- 4: Collins, M.O., et al. J. Biol. Chem. 280(7):5972-5982(2005)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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