MMP3 Antibody
CATALOG NUMBER: 22-091- Clonality: Polyclonal
- Tested Applications: IF, IHC, WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: A synthetic peptide of human MMP3
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, IHC, WB
- APPLICATION NOTE: WB: 1:500 - 1:1000
IHC: 1:20 - 1:50
IF: 1:20 - 1:50 - POSITIVE CONTROL 1: HepG2
- POSITIVE CONTROL 2: Raji
- POSITIVE CONTROL 3: Ramos
- PREDICTED MOLECULAR WEIGHT: Observed: 56kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C (regular) or -20°C (long term). Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: MMP3
- ADDITIONAL NAMES: CHDS6, matrix metallopeptidase 3 (stromelysin 1, progelatinase), matrix metalloproteinase 3 (stromelysin 1, matrix metalloproteinase-3, MGC126102, MGC126103, MGC126104, MMP3, MMP-3, OTTHUMP00000045949, proteoglycan, SL-1, STMY, STMY1, STR1
- NCBI GENE ID NUMBER: 4314
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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