MME Antibody
CATALOG NUMBER: 55-080- Clonality: Polyclonal
- Tested Applications: IHC-P, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse
- Conjugate: Unconjugated
- Size: 400 ul
Powered by BiozSpecifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: This MME antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721-747 amino acids from the C-terminal region of human MME.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 - PREDICTED MOLECULAR WEIGHT: 86 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: MME
- ADDITIONAL NAMES: Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 2411, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN
- Protein Accession Number: P08473
- PROTEIN GI NUMBER: 128062
- NCBI GENE ID NUMBER: 4311
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a common acute lymphocytic leukemiaantigen that is an important cell surface marker in the diagnosisof human acute lymphocytic leukemia (ALL). This protein is presenton leukemic cells of pre-B phenotype, which represent 85% of casesof ALL. This protein is not restricted to leukemic cells, however,and is found on a variety of normal tissues. It is a glycoproteinthat is particularly abundant in kidney, where it is present on thebrush border of proximal tubules and on glomerular epithelium. Theprotein is a neutral endopeptidase that cleaves peptides at theamino side of hydrophobic residues and inactivates several peptidehormones including glucagon, enkephalins, substance P, neurotensin,oxytocin, and bradykinin. This gene, which encodes a 100-kD type IItransmembrane glycoprotein, exists in a single copy of greater than45 kb. The 5' untranslated region of this gene is alternativelyspliced, resulting in four separate mRNA transcripts. The codingregion is not affected by alternative splicing. [provided byRefSeq].
- 1: Wang, S., et al. J. Neurochem. 115(1):47-57(2010)
- 2: Ikenaga, N., et al. Gastroenterology 139(3):1041-1051(2010)
- 3: Kim, H.S., et al. Histopathology 56(6):708-719(2010)
- 4: Toussaint, J., et al. PLoS ONE(8) (2010) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.
New & Featured Products
![HIV-1 p24 Antibody [10A2] (biotin)](https://www.prosci-inc.com/wp-content/uploads/2023/01/HIV-1-p24-Antibody-10A2_WB_PM-7371.gif){kind=small}
HIV-1 p24 Antibody [10A2] (biotin)
CATALOG NUMBER: PM-7371-biotin
![HIV-1 p24 Antibody [9D2F6] (biotin)](https://www.prosci-inc.com/wp-content/uploads/2023/01/HIV-1-p24-Antibody-9D2F6_WB_PM-7369.gif){kind=small}
HIV-1 p24 Antibody [9D2F6] (biotin)
CATALOG NUMBER: PM-7369-biotin
![HIV-1 p24 Antibody [8D7E11] (biotin)](https://www.prosci-inc.com/wp-content/uploads/2023/01/HIV-1-p24-Antibody-8D7E11_WB_PM-7367.gif){kind=small}
HIV-1 p24 Antibody [8D7E11] (biotin)
CATALOG NUMBER: PM-7367-biotin