MLXIPL Antibody
CATALOG NUMBER: 56-508- Clonality: Polyclonal
- Tested Applications: IHC-P, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: This MLXIPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-653 amino acids from the C-terminal region of human MLXIPL.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:2000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 93 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: MLXIPL
- ADDITIONAL NAMES: Carbohydrate-responsive element-binding protein, ChREBP, Class D basic helix-loop-helix protein 14, bHLHd14, MLX interactor, MLX-interacting protein-like, WS basic-helix-loop-helix leucine zipper protein, WS-bHLH, Williams-Beuren syndrome chromosomal region 14 protein, MLXIPL, BHLHD14, MIO, WBSCR14
- Protein Accession Number: Q9NP71
- PROTEIN GI NUMBER: 20140871
- NCBI GENE ID NUMBER: 51085
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a basic helix-loop-helix leucine zippertranscription factor of the Myc/Max/Mad superfamily. This proteinforms a heterodimeric complex and binds and activates, in aglucose-dependent manner, carbohydrate response element (ChoRE)motifs in the promoters of triglyceride synthesis genes. The geneis deleted in Williams-Beuren syndrome, a multisystem developmentaldisorder caused by the deletion of contiguous genes at chromosome7q11.23.
- 1: Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)
- 2: Johansen, C.T., et al. Nat. Genet. 42(8):684-687(2010)
- 3: Keebler, M.E., et al. Circ Cardiovasc Genet 3(4):358-364(2010)
- 4: Chidambaram, M., et al. Metab. Clin. Exp. (2010) In press :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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