Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat
- IMMUNOGEN: This MGAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-187 amino acids from the Central region of human MGAT1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 51 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: MGAT1
- ADDITIONAL NAMES: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, GNT-I, GlcNAc-T I, MGAT1, GGNT1, GLCT1, GLYT1, MGAT
- Protein Accession Number: P26572
- PROTEIN GI NUMBER: 311033399
- NCBI GENE ID NUMBER: 4245
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- There are believed to be over 100 differentglycosyltransferases involved in the synthesis of protein-bound andlipid-bound oligosaccharides.UDP-N-acetylglucosamine:alpha-3-D-mannosidebeta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzymeessential for the synthesis of hybrid and complex N-glycans. Theprotein, encoded by a single exon, shows typical features of a typeII transmembrane protein. The protein is believed to be essentialfor normal embryogenesis. Several variants encoding the sameprotein have been found for this gene.
- 1: Henquet, M., et al. Transgenic Res. 19(4):535-547(2010)
- 2: Johansson, A., et al. Obesity (Silver Spring) 18(4):803-808(2010)
- 3: Bousman, C.A., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (8), 1025-1049 (2009) :
- 4: Lowe, J.K., et al. PLoS Genet.(2), E1000365 (2009) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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