Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
- IMMUNOGEN: This Methionine Aminopeptidase 2 (METAP2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-467 amino acids from the C-terminal region of human Methionine Aminopeptidase 2 (METAP2).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 53 kDa
Properties
- PURIFICATION: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: METAP2
- ADDITIONAL NAMES: Methionine aminopeptidase 2 {ECO:0000255 | HAMAP-Rule:MF_03175}, MAP 2 {ECO:0000255 | HAMAP-Rule:MF_03175}, MetAP 2 {ECO:0000255 | HAMAP-Rule:MF_03175}, 341118 {ECO:0000255 | HAMAP-Rule:MF_03175}, Initiation factor 2-associated 67 kDa glycoprotein {ECO:0000255 | HAMAP-Rule:MF_03175}, p67 {ECO:0000255 | HAMAP-Rule:MF_03175}, p67eIF2 {ECO:0000255 | HAMAP-Rule:MF_03175}, Peptidase M {ECO:0000255 | HAMAP-Rule:MF_03175}, METAP2 {ECO:0000255 | HAMAP-Rule:MF_03175}
- Protein Accession Number: P50579
- PROTEIN GI NUMBER: 1703273
- NCBI GENE ID NUMBER: 10988
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The ADP-ribosylation factor (Arf) family are highly conserved members of the Ras superfamily of regulatory GTP-binding proteins. Arf proteins participate in routing of intracellular proteins to and within the Golgi complex. Cellular functions include maintenance of organelle integrity, coat protein assembly, as an activator of phospholipase D. The Arf family is divided functionally into the Arf and the Arf-like (Arl) proteins. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization.
- 1: Wang, J., et al., Biochemistry 42(17):5035-5042 (2003).
- 2: Datta, R., et al., Exp. Cell Res. 283(2):237-246 (2003).
- 3: Endo, H., et al., J. Biol. Chem. 277(29):26396-26402 (2002).
- 4: Kanno, T., et al., Lab. Invest. 82(7):893-901 (2002).
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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