Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 840-999 of human MERTK (NP_006334.2).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IF: 1:50 - 1:200 - POSITIVE CONTROL 1: 22Rv1
- POSITIVE CONTROL 2: Mouse liver
- POSITIVE CONTROL 3: Mouse kidney
- POSITIVE CONTROL 4: Mouse lung
- POSITIVE CONTROL 5: Mouse spleen
- POSITIVE CONTROL 6: Rat liver
- PREDICTED MOLECULAR WEIGHT: Observed: 160kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: MERTK
- ADDITIONAL NAMES: MERTK, c-mer proto-oncogene tyrosine kinase , MER, MGC133349, c-mer, MER receptor tyrosine kinase, STK kinase
- NCBI GENE ID NUMBER: 10461
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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