Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: MELK antibody was raised against a peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Western Blot: 1:500
- SPECIFICITY: This antibody detects endogenous level of total MELK protein.
- PREDICTED MOLECULAR WEIGHT: 74 kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: MELK
- ADDITIONAL NAMES: HPK38, hPK38, KIAA0175, hMELK
- Protein Accession Number: NP_055606.1
- PROTEIN GI NUMBER: 7661974
- NCBI GENE ID NUMBER: 9833
Background
- Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.
- 1: Seong H. -A., Gil M., Kim K. -T., Kim S. -J., Ha H. Biochem. J. 361:597-604 (2002) Vulsteke V., Beullens M., Boudrez A., Keppens S., Van Eynde A., Rider M. H., Stalmans W., Bollen M. J. Biol. Chem. 279:8642-8647 (2004)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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