Specifications
- SPECIES: Rat
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: QPDAVNAPLT CCYSFTGKMI PMSRLENYKR ITSSRCPKEA VVFVTKLKRE ICADPNKEWV QKYIRKLDQN QVRSETTVFY KIASTLRTSA PLNVNLTHKS EANASTLFST TTSSTSVEVT SMTEN
- BIOLOGICAL ACTIVITY: Biological activity was determined by its ability to chemoattract human monocytes using a concentration range of 10.0 - 100.0 ng/mL.
Properties
- PURITY: Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg). - PHYSICAL STATE: Lyophilized
- STORAGE CONDITIONS: The lyophilized MCP-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted MCP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing MCP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Additional Info
- NCBI OFFICIAL SYMBOL: Ccl2
- ADDITIONAL NAMES: MCP-1, Scya2, Sigje, Je, Mcp1, C-C motif chemokine 2, Immediate-early serum-responsive protein JE, MCP-1
- Protein Accession Number: NP_113718.1
- PROTEIN GI NUMBER: 13928714
- NCBI GENE ID NUMBER: 24770
Background
- The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant rat MCP-1 is a 14.0 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: This product is for research use only.
Shipping Info
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