MCOLN1 Antibody
CATALOG NUMBER: 57-113- Clonality: Polyclonal
- Tested Applications: IHC-P, WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Monkey, Mouse
- IMMUNOGEN: This MCOLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the C-terminal region of human MCOLN1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 65 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: MCOLN1
- ADDITIONAL NAMES: Mucolipin-1, MG-2, Mucolipidin, MCOLN1, ML4
- Protein Accession Number: Q9GZU1
- PROTEIN GI NUMBER: 50401163
- NCBI GENE ID NUMBER: 57192
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a memberof the transient receptorpotential (TRP) cation channel gene family. The transmembraneprotein localizes to intracellular vesicular membranes includinglysosomes, and functions in the late endocytic pathway and in theregulation of lysosomal exocytosis. The channel is permeable toCa(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changesin Ca(2+) concentration. Mutations in this gene result inmucolipidosis type IV.
- 1: Eichelsdoerfer, J.L., et al. J. Biol. Chem. 285(45):34304-34308(2010)
- 2: Curcio-Morelli, C., et al. J. Cell. Physiol. 222(2):328-335(2010)
- 3: Vergarajauregui, S., et al. J. Biol. Chem. 284(52):36357-36366(2009)
- 4: Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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