MARCH11 Antibody
CATALOG NUMBER: 57-285- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse, Rat
- IMMUNOGEN: This MARCH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human MARCH11.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 44 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: MARCH11
- ADDITIONAL NAMES: E3 ubiquitin-protein ligase MARCH11, 632-, Membrane-associated RING finger protein 11, Membrane-associated RING-CH protein XI, MARCH-XI, MARCH11
- Protein Accession Number: A6NNE9
- NCBI GENE ID NUMBER: 441061
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- MARCH11 is a member of the MARCH family of membrane-boundE3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin(see MIM 191339) to target lysines in substrate proteins, therebysignaling their intracellular transport. March11 appears to have arole in ubiquitin-mediated protein sorting in the trans-Golginetwork (TGN)-multivesicular body (MVB) transport pathway (Morokumaet al., 2007 [PubMed 17604280]).
- 1: Rose, J. Phd, et al. Mol. Med. (2010) In press :
- 2: Morokuma, Y., et al. J. Biol. Chem. 282(34):24806-24815(2007)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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