MAML1 Antibody
CATALOG NUMBER: 55-913- Clonality: Polyclonal
- Tested Applications: Flow, WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This MAML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-225 amino acids from the Central region of human MAML1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 108 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: MAML1
- ADDITIONAL NAMES: Mastermind-like protein 1, Mam-1, MAML1 (HGNC:13632)
- Protein Accession Number: Q92585
- PROTEIN GI NUMBER: 68565602
- NCBI GENE ID NUMBER: 9794
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This protein is the human homolog of mastermind, aDrosophila protein that plays a role in the Notch signaling pathwayinvolved in cell-fate determination. There is in vitro evidencethat the human homolog forms a complex with the intracellularportion of human Notch receptors and can increase expression of aNotch-induced gene. This evidence supports its proposed function asa transcriptional co-activator in the Notch signaling pathway.
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Lindberg, M.J., et al. FASEB J. 24(7):2396-2404(2010)
- 3: Hao, L., et al. Oncogene 29(2):201-213(2010)
- 4: Saint Just Ribeiro, M., et al. Curr. Protein Pept. Sci. 10(6):570-576(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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