MAFA Antibody
CATALOG NUMBER: 63-946- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse
- IMMUNOGEN: This MAFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-311 amino acids from the C-terminal region of human MAFA.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 37 kDa
Properties
- PURIFICATION: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: MAFA
- ADDITIONAL NAMES: Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
- Protein Accession Number: Q8NHW3
- PROTEIN GI NUMBER: 296435511
- NCBI GENE ID NUMBER: 389692
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene.
- 1: Kondo, T., et al. Mol. Endocrinol. 23(8):1281-1290(2009)
- 2: Kaneto, H., et al. Adv. Drug Deliv. Rev. 61 (7-8), 489-496 (2009)
- 3: Garin, I., et al. Diabet. Med. 26(7):746-748(2009)
- 4: Vanderford, N.L., et al. Arch. Biochem. Biophys. 480(2):138-142(2008)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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