Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human LHCGR (NP_000224.2).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, WB
- APPLICATION NOTE: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200 - POSITIVE CONTROL 1: NCI-H460
- POSITIVE CONTROL 2: HepG2
- POSITIVE CONTROL 3: Jurkat
- POSITIVE CONTROL 4: Mouse lung
- POSITIVE CONTROL 5: Mouse ovary
- POSITIVE CONTROL 6: Rat liver
- PREDICTED MOLECULAR WEIGHT: Observed: 70-78kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: LHCGR
- ADDITIONAL NAMES: LHCGR, luteinizing hormone/choriogonadotropin receptor, LCGR, LGR2, LHR, hLHR, luteinizing hormone receptor, lutropin/choriogonadotropin receptor, LH receptor, CG receptor, LHRHR
- NCBI GENE ID NUMBER: 3973
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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