Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This Leo1-S151 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-158 amino acids from the N-terminal region of human Leo1-S151.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 75 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: LEO1
- ADDITIONAL NAMES: RNA polymerase-associated protein LEO1, Replicative senescence down-regulated leo1-like protein, LEO1, RDL
- Protein Accession Number: Q8WVC0
- PROTEIN GI NUMBER: 74751545
- NCBI GENE ID NUMBER: 123169
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366),and PAF1 (MIM 610506) form the PAF protein complex that associateswith the RNA polymerase II subunit POLR2A (MIM 180660) and with ahistone methyltransferase complex (Rozenblatt-Rosen et al., 2005[PubMed 15632063]).
- 1: Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- 2: Olsen, J.V., et al. Cell 127(3):635-648(2006)
- 3: Olsen, J.V., et al. Cell 127(3):635-648(2006)
- 4: Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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