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LBP Antibody
LBP Antibody

LBP Antibody

CATALOG NUMBER: 29-596
  • Clonality: Polyclonal
  • Tested Applications: ELISA, WB
  • Host Species: Rabbit
  • Species Reactivity: Human
  • Conjugate: Unconjugated
  • Size: 100 ul

Specifications

  • HOST SPECIES: Rabbit
  • SPECIES REACTIVITY: Human
  • IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LBP.
  • CONJUGATE: Unconjugated
  • TESTED APPLICATIONS: ELISA, WB
  • APPLICATION NOTE: LBP antibody can be used for detection of LBP by ELISA at 1:62500. LBP antibody can be used for detection of LBP by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
  • POSITIVE CONTROL 1: Cat. No. 1211 - HepG2 Cell Lysate
  • PREDICTED MOLECULAR WEIGHT: 51 kDa

Properties

  • PURIFICATION: Antibody is purified by peptide affinity chromatography method.
  • CLONALITY: Polyclonal
  • PHYSICAL STATE: Liquid
  • BUFFER: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  • CONCENTRATION: batch dependent
  • STORAGE CONDITIONS: For short periods of storage (days) store at 4°C. For longer periods of storage, store LBP antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

  • NCBI OFFICIAL SYMBOL: LBP
  • ADDITIONAL NAMES: LBP, MGC22233, BPIFD2
  • Protein Accession Number: NP_004130
  • PROTEIN GI NUMBER: 31652249
  • NCBI GENE ID NUMBER: 3929
  • USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background

  • LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.
  • 1: Knapp, S., (2006) J. Immunol. 176 (5), 3189-3195.

Disclaimer

  • FOR RESEARCH USE ONLY
    For additional information, visit ProSci's Terms & Conditions Page.
  • Disclaimer: This product is for research use only.

CATALOG NUMBER: 29-596

  • Size: 100 ul
  • List Price: $475.00
Datasheet
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