KRAS Antibody
CATALOG NUMBER: 14-182- Clonality: Polyclonal
- Tested Applications: IF, IHC, IP, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 50 uL
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant protein of human KRAS
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, IHC, IP, WB
- APPLICATION NOTE: WB: 1:500 - 1:1000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
IP: 1:50 - 1:200 - POSITIVE CONTROL 1: A-549
- POSITIVE CONTROL 2: HeLa
- POSITIVE CONTROL 3: Raji
- POSITIVE CONTROL 4: Mouse spleen
- POSITIVE CONTROL 5: Mouse lung
- POSITIVE CONTROL 6: Rat brain
- PREDICTED MOLECULAR WEIGHT: Observed: 22kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: KRAS
- ADDITIONAL NAMES: KRAS, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS3, RASK2, NS, CFC2
- NCBI GENE ID NUMBER: 3845
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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