Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Mouse
- IMMUNOGEN: A synthetic peptide corresponding to an internal region between amino acids 200-299.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, IHC, WB
- APPLICATION NOTE: ELISA, Western (immuno) blotting, Immunostaining (in testing)
Properties
- PURIFICATION: Affinity Purified
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- CONCENTRATION: batch dependent
Additional Info
- NCBI OFFICIAL SYMBOL: Kmo
- ADDITIONAL NAMES: 317G22.1, KMO_HUMAN, Kynurenine 3 hydroxylase, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase), Kynurenine 3 monooxygenase, Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, RP1-317G22.1, AI046660,
- Protein Accession Number: EDL13209
- PROTEIN GI NUMBER: 81879610
- NCBI GENE ID NUMBER: 98256
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). The enzyme is required for synthesis of quinolinic acid. Quinolinic acid ia a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development.
- 1: Eniko Vamosa, Arpad Pardutza, Peter Klivenyia, Jozsef Toldib and Laszlo Vecsei, The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection. 2009 Journal of the Neurological Sciences Article in Press, Corrected Proof available on line
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: This product is for research use only.
Shipping Info
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