Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: This KLF12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human KLF12.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 44 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: KLF12
- ADDITIONAL NAMES: Krueppel-like factor 12, Transcriptional repressor AP-2rep, KLF12, AP2REP
- Protein Accession Number: Q9Y4X4
- PROTEIN GI NUMBER: 91771555
- NCBI GENE ID NUMBER: 11278
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Activator protein-2 alpha (AP-2 alpha) is adevelopmentally-regulated transcription factor and importantregulator of gene expression during vertebrate development andcarcinogenesis. The protein encoded by this gene is a member of theKruppel-like zinc finger protein family and can repress expressionof the AP-2 alpha gene by binding to a specific site in the AP-2alpha gene promoter. Repression by the encoded protein requiresbinding with a corepressor, CtBP1. Two transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
- 1: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- 2: Eyre, S., et al. Ann. Rheum. Dis. 69(7):1407-1408(2010)
- 3: Wieczorek, S., et al. J. Mol. Med. 88(4):413-421(2010)
- 4: Petersen, G.M., et al. Nat. Genet. 42(3):224-228(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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