Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human KARS (NP_005539.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
- POSITIVE CONTROL 1: HepG2
- POSITIVE CONTROL 2: Jurkat
- POSITIVE CONTROL 3: HeLa
- POSITIVE CONTROL 4: 293T
- POSITIVE CONTROL 5: Mouse heart
- POSITIVE CONTROL 6: Mouse kidney
- PREDICTED MOLECULAR WEIGHT: Observed: 75kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: KARS
- ADDITIONAL NAMES: KARS, KRS, KARS1, KARS2, CMTRIB, DFNB89
- NCBI GENE ID NUMBER: 3735
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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