Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human JUP (NP_002221.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, IP, WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
IP: 1:50 - 1:100 - POSITIVE CONTROL 1: MCF7
- POSITIVE CONTROL 2: 293T
- POSITIVE CONTROL 3: Mouse lung
- PREDICTED MOLECULAR WEIGHT: Observed: 82kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: JUP
- ADDITIONAL NAMES: Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, CTNNG, DP3
- NCBI GENE ID NUMBER: 3728
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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