ITPR3 Antibody
CATALOG NUMBER: 45-786- Clonality: Polyclonal
- Tested Applications: E
- Host Species: Goat
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Goat
- HOMOLOGY: Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Dog, Cow
- IMMUNOGEN: The immunogen for this antibody is: C-DKKERPTDEEGFLH
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E
- APPLICATION NOTE: Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Preliminary experiments gave an approx 60kDa band in Human Adipose, Colon, Duodenum, Heart and Liver lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 304kDa according to NP_002215.1. The 60kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
- SPECIFICITY: No cross-reactivity expected with other types of ITPR
Properties
- PURIFICATION: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
- CONCENTRATION: 500 ug/mL
- STORAGE CONDITIONS: Aliquot and store at -20°C. Minimize freezing and thawing.
Additional Info
- NCBI OFFICIAL SYMBOL: ITPR3
- ADDITIONAL NAMES: ITPR3, inositol 1,4,5-triphosphate receptor, type 3 , HGNC:6182, FLJ36205, IP3R, IP3R3
- Protein Accession Number: NP_002215.2
- PROTEIN GI NUMBER: 4504795
- NCBI GENE ID NUMBER: 3710
Background
- 1: Futatsugi A, Nakamura T, Yamada MK, Ebisui E, Nakamura K, Uchida K, Kitaguchi T, Takahashi-Iwanaga H, Noda T, Aruga J, Mikoshiba K. IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Science. 2005 Sep 30;309(5744):2232-4.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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