Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human ITPA (NP_258412.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
- POSITIVE CONTROL 1: U-87MG
- POSITIVE CONTROL 2: HT-29
- POSITIVE CONTROL 3: Mouse small intestine
- POSITIVE CONTROL 4: Mouse heart
- POSITIVE CONTROL 5: Rat liver
- PREDICTED MOLECULAR WEIGHT: Observed: 21kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: ITPA
- ADDITIONAL NAMES: Inosine triphosphate pyrophosphatase {ECO:0000255 | HAMAP-Rule:MF_03148}, ITPase {ECO:0000255 | HAMAP-Rule:MF_03148}, Inosine triphosphatase {ECO:0000255 | HAMAP-Rule:MF_03148}, 36119 {ECO:0000255 | HAMAP-Rule:MF_03148}, Non-canonical purine NTP pyrophosphatase {ECO:0000255 | HAMAP-Rule:MF_03148}, Non-standard purine NTP pyrophosphatase {ECO:0000255 | HAMAP-Rule:MF_03148}, Nucleoside-triphosphate diphosphatase {ECO:0000255 | HAMAP-Rule:MF_03148}, Nucleoside-triphosphate pyrophosphatase {ECO:0000255 | HAMAP-Rule:MF_03148}, NTPase {ECO:0000255 | HAMAP-Rule:MF_03148}, Putative oncogene protein hlc14-06-p, ITPA {ECO:0000255 | HAMAP-Rule:MF_03148}, C20orf37
- NCBI GENE ID NUMBER: 3704
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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