Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse
- IMMUNOGEN: This ITGA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-602 amino acids from the Central region of human ITGA5.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 115 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: ITGA5
- ADDITIONAL NAMES: Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e, Integrin alpha-5 heavy chain, Integrin alpha-5 light chain, ITGA5, FNRA
- Protein Accession Number: P08648
- PROTEIN GI NUMBER: 23831237
- NCBI GENE ID NUMBER: 3678
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The product of this gene belongs to the integrin alphachain family. Integrins are heterodimeric integral membraneproteins composed of an alpha chain and a beta chain. This geneencodes the integrin alpha 5 chain. Alpha chain 5 undergoespost-translational cleavage in the extracellular domain to yielddisulfide-linked light and heavy chains that join with beta 1 toform a fibronectin receptor. In addition to adhesion, integrins areknown to participate in cell-surface mediated signalling. [providedby RefSeq].
- 1: Hutton, M.L., et al. Infect. Immun. 78(11):4523-4531(2010)
- 2: Fang, Z., et al. J. Cell. Biochem. 110(5):1130-1141(2010)
- 3: Lobert, V.H., et al. Dev. Cell 19(1):148-159(2010)
- 4: Caicedo-Carvajal, C.E., et al. PLoS ONE(7), E11830 (2010) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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