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- SPECIES: Human
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK EMSKRSP
- BIOLOGICAL ACTIVITY: Biological activity was determined by its ability to chemoattract human T - Lymphocytes using a concentration of 10 - 50 ng/mL.
Properties
- PURITY: Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg). - PHYSICAL STATE: Lyophilized
- STORAGE CONDITIONS: The lyophilized IP-10 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IP-10 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IP-10 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Additional Info
- NCBI OFFICIAL SYMBOL: CXCL10
- ADDITIONAL NAMES: C7, IFI10, INP10, IP-10, crg-2, mob-1, SCYB10, gIP-10, C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10
- Protein Accession Number: NP_001556.2
- PROTEIN GI NUMBER: 149999382
- NCBI GENE ID NUMBER: 3627
Background
- IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant human IP-10 is an 8.5 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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