Il6ra Antibody
CATALOG NUMBER: 43-423- Clonality: Polyclonal
- Tested Applications: E
- Host Species: Goat
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Goat
- HOMOLOGY: Expected Species Reactivity based on sequence homology: Mouse, Rat
- IMMUNOGEN: The immunogen for this antibody is: C-YLLQFQLRYRPVWSK
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E
- APPLICATION NOTE: Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Preliminary experiments in Mouse Spleen and Thymus lysates and in lysates of cell lines NIH3T3 and NSO gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
- SPECIFICITY: This antibody is expected to recognize all reported isoforms (NP_000556.1; NP_852004.1). The sequence of the immunizing peptide corresponds with a part of the extracellular domain.
Properties
- PURIFICATION: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
- CONCENTRATION: 500 ug/mL
- STORAGE CONDITIONS: Aliquot and store at -20°C. Minimize freezing and thawing.
Additional Info
- NCBI OFFICIAL SYMBOL: Il6ra
- ADDITIONAL NAMES: Il6ra, interleukin 6 receptor, alpha, CD126, IL-6R, Il6r, MGC30256, IL-6 receptor alpha chain, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, IL-6R
- Protein Accession Number: NP_034689.2
- PROTEIN GI NUMBER: 110431356
- NCBI GENE ID NUMBER: 16194
Background
- 1: Boulanger MJ, Chow DC, Brevnova EE, Garcia KC.Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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