IL5RA Antibody
CATALOG NUMBER: 60-404- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This IL5RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-420 amino acids from the C-terminal region of human IL5RA.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 48 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: IL5RA
- ADDITIONAL NAMES: Interleukin-5 receptor subunit alpha, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5R-alpha, IL-5RA, CDw125, CD125, IL5RA, IL5R
- Protein Accession Number: Q01344
- PROTEIN GI NUMBER: 116242525
- NCBI GENE ID NUMBER: 3568
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The protein encoded by this gene is an interleukin 5specific subunit of a heterodimeric cytokine receptor. The receptoris comprised of a ligand specific alpha subunit and a signaltransducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the betasubunit. The beta subunit is activated by the ligand binding, andis required for the biological activities of IL5. This protein hasbeen found to interact with syndecan binding protein (syntenin),which is required for IL5 mediated activation of the transcriptionfactor SOX4. Six alternatively spliced transcript variants encodingthree distinct isoforms have been reported.
- 1: Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
- 2: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 3: Beckers, M.M., et al. Eur. J. Intern. Med. 21(4):289-292(2010)
- 4: Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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