Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL33.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, WB
- APPLICATION NOTE: IL33 antibody can be used for detection of IL33 by ELISA at 1:62500. IL33 antibody can be used for detection of IL33 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- POSITIVE CONTROL 1: 293T Cell Lysate
- PREDICTED MOLECULAR WEIGHT: 31 kDa
Properties
- PURIFICATION: Antibody is purified by peptide affinity chromatography method.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: For short periods of storage (days) store at 4°C. For longer periods of storage, store IL33 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: IL33
- ADDITIONAL NAMES: IL33, C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2, IL1F11
- Protein Accession Number: NP_254274
- PROTEIN GI NUMBER: 15559209
- NCBI GENE ID NUMBER: 90865
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL33 induces T helper type 2-associated cytokines.
- 1: Humphreys, N.E., (2008) J. Immunol. 180 (4), 2443-2449.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: This product is for research use only.
Shipping Info
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