IL1R2 Antibody
CATALOG NUMBER: 55-587- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This IL1R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the Central region of human IL1R2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 45 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: IL1R2
- ADDITIONAL NAMES: Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, CD121b, Interleukin-1 receptor type 2, membrane form, mIL-1R2, mIL-1RII, Interleukin-1 receptor type 2, soluble form, sIL-1R2, sIL-1RII, IL1R2, IL1RB
- Protein Accession Number: P27930
- PROTEIN GI NUMBER: 124310
- NCBI GENE ID NUMBER: 7850
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The protein encoded by this gene is a cytokine receptorthat belongs to the interleukin 1 receptor family. This proteinbinds interleukin alpha (IL1A), interleukin beta (IL1B), andinterleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoyreceptor that inhibits the activity of its ligands. Interleukin 4(IL4) is reported to antagonize the activity of interleukin 1 byinducing the expression and release of this cytokine. This gene andthree other genes form a cytokine receptor gene cluster onchromosome 2q12. Two alternatively spliced transcript variantsencoding the same protein have been reported.
- 1: Giroux, S., et al. Bone 47(5):975-981(2010)
- 2: Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
- 3: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 4: Chen, C., et al. Rheumatol. Int. (2010) In press :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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