Specifications
- HOST SPECIES: Chicken
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: 37-193
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, WB
- APPLICATION NOTE: IL17 antibody can be used for the detection of IL-17 by ELISA, Western blot, may also work for IHC and ICC.
- PREDICTED MOLECULAR WEIGHT: 17.5 kDa (calculated)
Properties
- PURIFICATION: Antigen affinity-purified
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Phosphate-Buffered Saline. No preservatives added.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: IL17A antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: IL18
- ADDITIONAL NAMES: IGIF, IL1F4, Interleukin-18, Iboctadekin, IL-18, IGIF, IL-1g,
- Protein Accession Number: NP_001553.1
- PROTEIN GI NUMBER: 4504653
- NCBI GENE ID NUMBER: 3606
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Interleukin 17; cytotoxic T-lymphocyte-associated serine esterase 8. This protein is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-κB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis
- 1: Nakae, S., Saijo, S., Horai, R., Sudo, K., Mori, S., Iwakura, Y. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc. Nat. Acad. Sci. 100: 5986-5990, 2003.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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