- Trial Size
IFTLD1 Antibody
CATALOG NUMBER: 6447- Clonality: Polyclonal
- Tested Applications: E, IHC-P, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 0.02 mg | 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: IFLTD1 antibody was raised against an 19 amino acid synthetic peptide near the center of human IFLTD1.
The immunogen is located within amino acids 200 - 250 of IFTLD1. - CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E, IHC-P, WB
- APPLICATION NOTE: IFLTD1 antibody can be used for detection of IFLTD1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. - SPECIFICITY: At least four isoforms of IFLTD1 are known to exist; this antibody will detect all but isoform 4
- POSITIVE CONTROL 1: Cat. No. 1462 - Rat Lung Tissue Lysate
Properties
- PURIFICATION: IFTLD1 Antibody is affinity chromatography purified via peptide column.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: IFTLD1 Antibody is supplied in PBS containing 0.02% sodium azide.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: IFTLD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: IFLTD1
- ADDITIONAL NAMES: IFTLD1 Antibody: PAS1C1, Intermediate filament tail domain-containing protein 1
- Protein Accession Number: NP_001139200
- PROTEIN GI NUMBER: 224593273
- NCBI GENE ID NUMBER: 160492
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- IFTLD1 Antibody: The intermediate filament tail domain-containing protein (IFLTD1) was initially identified as a candidate gene for pulmonary adenoma susceptibility 1 gene in mice. Transcripts of the gene were only detected in mouse lung tissue from strains carrying the Pas1-susceptible allele. Expression of different alleles of this gene in lung cancer cell lines resulted in different levels of colony formation in in vitro colony formation assays, suggesting that allelic variants of this gene can modulate growth of human cancer cells.
- 1: Wang M, Lemon WJ, Liu G, et al. Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines. Cancer Res. 2003; 63:3317-24.
- 2: Wang M, Futamura M, Wang Y, et al. Pasc1 is a candidate for the mouse pulmonary adenoma susceptibility 1 locus. Oncogene 2005; 24:1958-63.
- 3: Galbiati F, Pettinicchio A, Dragani TA, et al. Allelic effects of mouse Pas candidate genes in human lung cancer cell lines. Cancer Lett. 244:176-81.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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