Specifications
- HOST SPECIES: Rat
- SPECIES REACTIVITY: Mouse
- CONJUGATE: FITC
- TESTED APPLICATIONS: Flow
- SPECIFICITY: The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties.
Properties
- PURIFICATION: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- CLONALITY: Monoclonal
- ISOTYPE: Rat IgG1, kappa
- PHYSICAL STATE: liquid
- BUFFER: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Additional Info
- NCBI OFFICIAL SYMBOL: Ifng
- ADDITIONAL NAMES: Ifg, IFN-g, Ifng
- NCBI GENE ID NUMBER: 15978
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-gamma) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-gamma plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. IFN- gamma is the primary cytokine that defines Th-1 cells.The biological activity of IFN-gamma is not affected by glycosylation.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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