HSD11B1 Antibody
CATALOG NUMBER: 45-748- Clonality: Polyclonal
- Tested Applications: ELISA, WB
- Host Species: Goat
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Goat
- SPECIES REACTIVITY: Human
- HOMOLOGY: Expected Species Reactivity based on sequence homology: Cow
- IMMUNOGEN: The immunogen for this antibody is: CTSYNMDRFINK
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, WB
- APPLICATION NOTE: Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot:Approx 35kDa band observed in Human Liver lysates (calculated MW of 32.4kDa according to NP_005516.1 and NP_861420.1). Recommended concentration: 0.3-1ug/ml.
- SPECIFICITY: This antibody is expected to recognise human HSD11B1 protein. Both NP_005516.1 and NP_861420.1 variants encode the same protein.
- POSITIVE CONTROL 1: Cat. No. 1304 - Human Liver Tissue Lysate
Properties
- PURIFICATION: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
- CONCENTRATION: 500 ug/mL
- STORAGE CONDITIONS: Aliquot and store at -20°C. Minimize freezing and thawing.
Additional Info
- NCBI OFFICIAL SYMBOL: HSD11B1
- ADDITIONAL NAMES: HSD11B1, HDL, 11-DH, HSD11L, MGC13539, 11-beta-HSD1, hydroxysteroid (11-beta) dehydrogenase 1, corticosteroid 11-beta-dehydrogenase isozyme 1, HSD11, HSD11B, SDR26C1, 11-beta-hydroxysteroid dehydrogenase 1, OTTHUMP00000034650, short chain dehydrogenase/reductase family 26C, member 1
- Protein Accession Number: NP_005516.1,NP_861420.1
- PROTEIN GI NUMBER: 5031765
- NCBI GENE ID NUMBER: 3290
Background
- 1: Paterson JM, Morton NM, Fievet C, Kenyon CJ, Holmes MC, Staels B, Seckl JR, Mullins JJ. Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. Proc Natl Acad Sci USA. 2004 May 4;101(18):7088-93. Epub 2004 Apr 26.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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