Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Dog, Human
- IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HOXD3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, IHC, WB
- APPLICATION NOTE: HOXD3 antibody can be used for detection of HOXD3 by ELISA at 1:62500. HOXD3 antibody can be used for detection of HOXD3 by western blot at 1.0-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- POSITIVE CONTROL 1: Cat. No. 1205 - Jurkat Cell Lysate
- PREDICTED MOLECULAR WEIGHT: 46 kDa
Properties
- PURIFICATION: Antibody is purified by peptide affinity chromatography method.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: For short periods of storage (days) store at 4°C. For longer periods of storage, store HOXD3 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: HOXD3
- ADDITIONAL NAMES: HOXD3, HOX4, HOX1D, HOX4A, Hox-4.1
- Protein Accession Number: NP_008829
- PROTEIN GI NUMBER: 19923391
- NCBI GENE ID NUMBER: 3232
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.
- 1: Boudreau, N.J., et al., (2004) J.Biol.Chem.279(6), 4862-4868.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: This product is for research use only.
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