HLA-DQA2 Antibody
CATALOG NUMBER: 60-924- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This HLA-DQA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human HLA-DQA2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 28 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: HLA-DQA2
- ADDITIONAL NAMES: HLA class II histocompatibility antigen, DQ alpha 2 chain, DX alpha chain, HLA class II histocompatibility antigen, DQ(6) alpha chain, HLA-DQA1, MHC class II DQA2, HLA-DQA2, HLA-DXA
- Protein Accession Number: P01906
- PROTEIN GI NUMBER: 122192
- NCBI GENE ID NUMBER: 3118
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene belongs to the HLA class II alpha chain family.The encoded protein forms a heterodimer with a class II beta chain.It is located in intracellular vesicles and plays a central role inthe peptide loading of MHC class II molecules by helping to releasethe CLIP molecule from the peptide binding site. Class II moleculesare expressed in antigen presenting cells (B lymphocytes, dendriticcells, macrophages) and are used to present antigenic peptides onthe cell surface to be recognized by CD4 T-cells. [provided byRefSeq].
- 1: Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
- 2: Hor, H., et al. Nat. Genet. 42(9):786-789(2010)
- 3: Petukhova, L., et al. Nature 466(7302):113-117(2010)
- 4: Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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