Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Virus
- IMMUNOGEN: Rabbit polyclonal HIV-1 p24 antibody was raised against a recombinant full-length HIV-1 p24 protein .
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E, WB
- APPLICATION NOTE: P24 antibody can be used for detection of p24 by Western blot at 0.5 - 1 μg/mL.
- SPECIFICITY: P24 antibody detects a 24 kDa recombinant protein.
- POSITIVE CONTROL 1: Cat. No. 95-153 - HIV-1 p24 Recombinant Protein
- PREDICTED MOLECULAR WEIGHT: 24 kDa
Properties
- PURIFICATION: HIV-1 p24 Antibody is affinity chromatography purified via peptide column.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: HIV-1 p24 Antibody is supplied in PBS containing 0.02% sodium azide.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: HIV-1 p24 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: GAG
- ADDITIONAL NAMES: HIV-1 p24 Antibody: Gag polyprotein, Pr55Gag, MA
- Protein Accession Number: AAB50258
- PROTEIN GI NUMBER: 327745
- NCBI GENE ID NUMBER: 155030
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- HIV-1 p24 Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix. The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein. The p24 is the major capsid protein of the virus and has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different strains.
- 1: Goto T, Nakai M, and Ikuta K. The life-cycle of human immunodeficiency virus type 1. Micron 1998; 29:123-38.
- 2: Freed EO. HIV-1 gag proteins: diverse functions in the virus life cycle. Virology 1998; 251:1-15.
- 3: Lindenburg CE, Stolte I, Langendam MW, et al. Long-term follow-up : no effect of therapeutic vaccination with HIV-1 p17/p24:Ty virus-like particles on HIV-1 disease progression. Vaccine 2002 ; 20 :2343-7.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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