Histone H3.1 (Ab 10) Antibody
CATALOG NUMBER: 79-555- Clonality: Polyclonal
- Tested Applications: IF, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Histone H3.1 (Ab-10) antibody was raised against a peptide sequence around aa.8~12 (R-K-S-T-G) derived from Human Histone H3.1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, WB
- APPLICATION NOTE: Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
- SPECIFICITY: This antibody detects endogenous level of total Histone H3.1 protein.
- PREDICTED MOLECULAR WEIGHT: 17 kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: HIST1H3D
- ADDITIONAL NAMES: H3/b, H3FB, H3/a, H3/c, H3/d, H3/f, H3/h
- Protein Accession Number: NP_003521.2
- PROTEIN GI NUMBER: 21071021
- NCBI GENE ID NUMBER: 8351
Background
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- 1: Workman, J. L. and Kingston, R. E. (1998) Annu Rev Biochem 67, 545-79. Hansen, J. C. et al. (1998) Biochemistry 37, 17637-41. Strahl, B. D. and Allis, C. D. (2000) Nature 403, 41-5. Cheung, P. et al. (2000) Cell 103, 263-71.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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