Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Monkey
- IMMUNOGEN: This HERV-FRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the N-terminal region of human HERV-FRD.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 60 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: ERVFRD-1
- ADDITIONAL NAMES: Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD, HERV-FRD_6p241 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERVFRD-1, ERVFRDE1
- Protein Accession Number: P60508
- PROTEIN GI NUMBER: 44887864
- NCBI GENE ID NUMBER: 405754
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Human endogenous retroviruses (HERVs) make upapproximately 8% of the human genome. Although most HERVs arenonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRDenvelope (env) proteins can induce cell-cell fusion when expressedin cells possessing appropriate receptors (Blaise et al., 2003[PubMed 14557543]).
- 1: Vargas, A., et al. J. Mol. Biol. 392(2):301-318(2009)
- 2: Chen, C.P., et al. Biol. Reprod. 79(5):815-823(2008)
- 3: Malassine, A., et al. Retrovirology 5,(2008) :
- 4: Mangeney, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(51):20534-20539(2007)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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