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HER2 Antibody [HRB2/258]
CATALOG NUMBER: 33-123- Clonality: Monoclonal
- Tested Applications: Flow, IF, WB
- Host Species: Mouse
- Species Reactivity: Human, Rat
- Conjugate: Unconjugated
- Size: 100 ug
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- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human, Rat
- IMMUNOGEN: Recombinant human protein was used as the immunogen for this ErbB2 antibody.(1)
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, IF, WB
- APPLICATION NOTE: Flow Cytometry: 0.5-1 ug/million cells
IF: 0.5-1 ug/ml
Variations in protocols, secondaries and substrates may require the antibody to be titered for optimal performance.1. This ErbB2 antibody binds to the extracellular/cell surface region of the protein.
Properties
- PURIFICATION: Protein G purified
- CLONALITY: Monoclonal
- ISOTYPE: IgG2a, kappa
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
- CONCENTRATION: 0.2 mg/mL
- STORAGE CONDITIONS: Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: ERBB2
- ADDITIONAL NAMES: erbB-2 Antibody: NEU, NGL, HER2, TKR1, CD340, HER-2, MLN 19, HER-2/neu, MLN19, NEU, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein
- NCBI GENE ID NUMBER: 2064
- USER NOTE: Optimal dilutions for each application to be determined by the researcher
Background
- This antibody recognizes a protein of 185kDa, which is identified as HER2 / ErbB2. Its epitope is localized in the extracellular domain. ErbB2 is a member of the EGFR family. This antibody is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. ErbB2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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