Guanylyl Cyclase beta 1 Antibody
CATALOG NUMBER: 63-445- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This GUCY1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected between 589-619 amino acids of human GUCY1B3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 71 kDa
Properties
- PURIFICATION: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: GUCY1B3
- ADDITIONAL NAMES: Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit, GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
- Protein Accession Number: Q02153
- PROTEIN GI NUMBER: 399328
- NCBI GENE ID NUMBER: 2983
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.
- 1: Russwurm, M., et al., J. Biol. Chem. 276(48):44647-44652 (2001).
- 2: Lucas, K.A., et al., Pharmacol. Rev. 52(3):375-414 (2000).
- 3: Papapetropoulos, A., et al., J. Cell. Physiol. 167(2):213-221 (1996).
- 4: Giuili, G., et al., Hum. Genet. 91(3):257-260 (1993).
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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